Documents & Downloads

nAChR antagonist 3

α7 nAChR Antagonist

nAChR antagonist 3 is a selective antagonist of the α7 nicotinic acetylcholine receptor, demonstrating an IC50 of 0.86 μM. It exhibits protective effects against toxicity induced by paraoxon, making it a valuable tool for studying organophosphate poisoning. This compound is suitable for research applications focusing on neuroprotection and receptor modulation associated with cholinergic signaling pathways.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	3114746-65-2
Applications	α7 nAChR Antagonist
Formula	C₁₆H₂₁Br₂N₃O
Molecular Weight	431.17
SMILES	CC(C)(N1CCC2(CC1)NC(C3=CC(Br)=CC(Br)=C3)=NO2)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.