Fig. 1 · Structure
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nAChR-IN-2
nAChR Inhibitor
nAChR-IN-2 is an inhibitor of insect nicotinic acetylcholine receptors (nAChR), targeting the acetylcholine binding site and the NCB/PCP binding site. It demonstrates an IC50 of 360 μM for α-bungarotoxin binding and 84 μM for Phencyclidine binding in honeybee head preparations. This compound is valuable for studying nAChR-mediated signaling pathways and their role in insect neurobiology. Research applications include investigating insecticide mechanisms and assessing the neurophysiological effects of nAChR modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3000-75-7 |
| Applications | nAChR Inhibitor |
| Formula | C8H12N2 |
| Molecular Weight | 136.19 |
| SMILES | CCNCC1=CC=CN=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.