nAChR-IN-2 is an inhibitor of insect nicotinic acetylcholine receptors (nAChR), targeting the acetylcholine binding site and the NCB/PCP binding site. It demonstrates an IC50 of 360 μM for α-bungarotoxin binding and 84 μM for Phencyclidine binding in honeybee head preparations. This compound is valuable for studying nAChR-mediated signaling pathways and their role in insect neurobiology. Research applications include investigating insecticide mechanisms and assessing the neurophysiological effects of nAChR modulation.
nAChR-IN-2 is an inhibitor of insect nicotinic acetylcholine receptors (nAChR), targeting the acetylcholine binding site and the NCB/PCP binding site. It demonstrates an IC50 of 360 μM for α-bungarotoxin binding and 84 μM for Phencyclidine binding in honeybee head preparations. This compound is valuable for studying nAChR-mediated signaling pathways and their role in insect neurobiology. Research applications include investigating insecticide mechanisms and assessing the neurophysiological effects of nAChR modulation.
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