Nadecnemab

Catalog No.: AT0029

Nadecnemab is an IgG4κ monoclonal antibody that targets GDNF family receptor alpha 3 (GFRA3), a receptor involved in neurotrophic signaling. Nadecnemab is suitable for research into chronic pain and osteoarthritis of the knee, particularly in models examining the GDNF–RET signaling axis.

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Grouped product items
Size	Price	Stock
1mg	$424.00	In stock
5mg	$1,060.00	In stock
10mg	$1,680.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	Nadecnemab is an IgG4κ monoclonal antibody that targets GDNF family receptor alpha 3 (GFRA3), a receptor involved in neurotrophic signaling. Nadecnemab is suitable for research into chronic pain and osteoarthritis of the knee, particularly in models examining the GDNF–RET signaling axis.
Targets	Glial cell derived neurotrophic factor family receptor alpha 3 (GFRA3)

Product Information

Catalog Num	AT0029
Molecular Weight	145500
CAS Number	2377679-19-9
Isotype	Human IgG4 (S228P) kappa, Isotype Control
Species	Human

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What are Biosimilar Antibodies?

Biosimilar antibodies are research-grade recombinant antibodies designed to closely resemble approved therapeutic antibodies in terms of amino acid sequence, structural characteristics, and biological activity. These antibodies are generated using recombinant expression technologies and retain the same variable regions as their corresponding reference therapeutics, thereby preserving target specificity and binding affinity. Owing to these properties, biosimilar antibodies serve as reliable and cost-effective research reagents for applications in drug discovery, pharmacological studies, and basic biomedical research. Research-grade biosimilar antibodies have been successfully expressed and functionally validated against a wide range of widely studied targets. These antibodies can be directly utilized as positive control reagents in drug discovery programs, as well as reference tools for rapid verification of the biological functions of target proteins in biochemical and cellular assays.