Documents & Downloads

Nafenodone

Antidepressant

Nafenodone is an antidepressant compound primarily targeting serotonin reuptake inhibition, leading to enhanced serotonergic neurotransmission. It has been shown to reduce the frequency and amplitude of smooth muscle contractions while prolonging the recovery time of the sinus node. Nafenodone effectively inhibits spontaneous mechanical activity in rat portal vein segments, with an IC50 of 1.4 μM, and can relax contractions induced by high potassium and noradrenaline. This compound is valuable for research into mood disorders and vascular smooth muscle function.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
CAS Number	92615-20-8
Applications	Antidepressant
Formula	C₂₀H₂₃NO
Molecular Weight	293.40
SMILES	O=C1C2=C(CCC1(CCN(C)C)C3=CC=CC=C3)C=CC=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.