Fig. 1 · Structure
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Naftopidil-d5
Stable Isotope
Naftopidil-d5 is a deuterium-labeled form of Naftopidil, a selective alpha-1 adrenoceptor antagonist. With inhibition constants (Kis) of 3.7 nM, 20 nM, and 1.2 nM for the human α1a, α1b, and α1d adrenoceptor subtypes respectively, Naftopidil exhibits significant antiproliferative effects. This reagent is particularly useful for research studies focused on benign prostatic hyperplasia and related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2747918-58-5 |
| Applications | Stable Isotope |
| Formula | C24H23D5N2O3 |
| Molecular Weight | 397.52 |
| Synonyms | KT-611-d5; BM-15275-d5 |
| SMILES | OC(C([2H])([2H])N1CCN(CC1)C2=C(OC)C=CC=C2)([2H])C([2H])([2H])OC3=CC=CC4=C3C=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.