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Naftopidil 2HCl

5-HT1A and α1-adrenergic receptor antagonist

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Catalog No. A10619

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Naftopidil Dihydrochloride 25mg A10619-25
Naftopidil Dihydrochloride 50mg A10619-50
Naftopidil Dihydrochloride 100mg A10619-100
Naftopidil Dihydrochloride 500mg A10619-500
Naftopidil 2HCl 10mM * 1mL in DMSO A10619-10mM-D

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Naftopidil 2HCl is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.

Naftopidil 2HCl

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Chemical Information

Catalog Num A10619
Actions Antagonist
M. Wt 465.4
Formula C24H28N2O3.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 57149-08-3
Synonyms Flivas, KT-611, Avishot

Biological Activity

Naftopidil 2HCl is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.
5-HT1A α1-adrenergic receptor
0.1 μM0.2 μM


Solubility (25°C) * In vitro DMSO 41 mg/mL (88.09 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (4.29 mM)
In vivo 0.5% CMC 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.49 mL 107.43 mL 214.87mL
0.5 mM 4.3 mL 21.49 mL 42.97 mL
1 mM 2.15 mL 10.74 mL 21.49 mL
5 mM 0.43 mL 2.15 mL 4.3 mL

*The above data is based on the productmolecular weight 465.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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