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Naloxonazine dihydrochloride

Catalog No.: A62341
Mu-opioid Receptor Antagonist
Naloxonazine dihydrochloride is a specific μ-opioid receptor antagonist with a reported IC50 of 5.4 nM. This compound not only inhibits μ-opioid receptor activity but also demonstrates anti-leishmanial properties, making it relevant for studies on pain management and parasitic infections. Its unique profile supports research applications in opioid receptor modulation and leishmaniasis treatment development.
Naloxonazine dihydrochloride 880759-65-9 Mu-opioid Receptor Antagonist
Grouped product items
Size Price Stock Qty
5mg
$145.00
In stock
10mg
$250.00
In stock
25mg
$485.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNaloxonazine dihydrochloride is a specific μ-opioid receptor antagonist with a reported IC50 of 5.4 nM. This compound not only inhibits μ-opioid receptor activity but also demonstrates anti-leishmanial properties, making it relevant for studies on pain management and parasitic infections. Its unique profile supports research applications in opioid receptor modulation and leishmaniasis treatment development.
Product Information
Catalog NumA62341
FormulaC38H44Cl2N4O6
Molecular Weight723.69
CAS Number880759-65-9
SMILESO[C@@]([C@@]1([H])CC2=CC=C3O)(CC/4)[C@@]5(CCN1CC=C)C2=C3O[C@@]5([H])C4=N\N=C(CC[C@]67O)\[C@@]8([H])[C@]6(CCN(CC=C)[C@]7([H])CC9=CC=C%10O)C9=C%10O8.Cl.Cl
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > Opioid Receptors