Fig. 1 · Structure
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Naloxone hydrochloride
Opioid Receptor Antagonist
Naloxone hydrochloride is a competitive antagonist of opioid receptors, primarily targeting the mu-opioid receptor. It is widely used in research to reverse opioid overdose effects, particularly respiratory depression. Additionally, caution should be exercised, as naloxone can induce side effects such as pulmonary edema and cardiac arrhythmias in certain conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 357-08-4 |
| Applications | Opioid Receptor Antagonist |
| Formula | C19H22ClNO4 |
| Molecular Weight | 363.84 |
| SMILES | OC1=C(O2)C([C@]([C@]2([H])C(CC3)=O)(CCN4CC=C)[C@]3(O)[C@H]4C5)=C5C=C1.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.