Fig. 1 · Structure

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Naloxone methiodide

Opioid Receptor Antagonist

Naloxone methiodide is a peripherally restricted, nonselective competitive antagonist of opioid receptors. Its lack of ability to penetrate the blood-brain barrier allows for targeted effects in peripheral tissues. This compound is primarily used in research applications investigating opioid receptor activity and the modulation of peripheral opioid effects, making it valuable for studying pain management and opioid-related responses.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 93302-47-7
Applications Opioid Receptor Antagonist
Formula C20H24INO4
Molecular Weight 469.31
SMILES
O[C@@]1(CCC2=O)[C@@]([C@@]2([H])OC3=C4O)(CC5)C3=C(C=C4)C[C@H]1[N@@+]5(C)CC=C.[I-]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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