Fig. 1 · Structure
Documents & Downloads
Naltrexone
Opioid Receptor Antagonist
Naltrexone is a long-acting antagonist of opioid receptors, including μ, κ, and δ subtypes. It effectively blocks the euphoric effects of exogenous opioids and diminishes alcohol cravings by antagonizing these receptors. Clinically, low doses of Naltrexone are utilized for chronic pain management, the treatment of inflammatory conditions, and potentially inhibiting tumor growth. Additionally, it is employed to alleviate intractable pruritus associated with psoriasis and atopic dermatitis, while its combination with Bupropion may contribute to reduced food cravings and body weight management.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 16590-41-3 |
| Applications | Opioid Receptor Antagonist |
| Formula | C20H23NO4 |
| Molecular Weight | 341.40 |
| SMILES | OC1=CC=C2C3=C1O[C@](C(CC4)=O)([H])[C@@]3(CCN5CC6CC6)[C@]4(O)[C@@]5([H])C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.