Napabucasin

Catalog No.: A13474

STAT inhibitor

Napabucasin

Napabucasin Chemical Structure

CAS NO. 83280-65-3

Napabucasin is an orally-administered small molecule which can block cancer stem cell (CSC) self-renewal and induces cell death in CSCs as well as non-stem cancer cells.

Availability: In stock

Package Price Qty
10 mg
$90.00
25 mg
$180.00
50 mg
$225.00
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Biological Activity

Napabucasin is an orally-administered small molecule which can block cancer stem cell (CSC) self-renewal and induces cell death in CSCs as well as non-stem cancer cells.
Targets
Stat3
In vitro (25°C) DMSO 10 mg/mL (41.63 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+40% PEG 300+5% Tween 80+ddH2O 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 41.63 mL 208.15 mL 416.3 mL
0.5 mM 8.33 mL 41.63 mL 83.26 mL
1 mM 4.16 mL 20.82 mL 41.63 mL
5 mM 0.83 mL 4.16 mL 8.33 mL

*The above data is based on the productmolecular weight 240.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13474
Actions Inhibitor
CAS No. 83280-65-3
Formula C14H8O4
M. Wt 240.21
Purity >98%
Synonyms BBI 608, BBI608, BBI-608
SMILES O=C(C1=C2OC(C(C)=O)=C1)C3=C(C2=O)C=CC=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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