Fig. 1 · Structure
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Naphthyridine carbamate dimer
DNA Molecular Glue
Naphthyridine carbamate dimer (NCD) is a DNA molecular glue that facilitates specified structural alterations in target functional DNA sequences, thereby modulating their biological activity. This reagent is instrumental in research applications that focus on gene regulation, DNA-protein interactions, and the design of programmable nucleic acid-based systems. Its unique mechanism enables researchers to explore novel therapeutic strategies and develop innovative tools in molecular biology and genetics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 864627-58-7 |
| Applications | DNA Molecular Glue |
| Formula | C26H29N7O4 |
| Molecular Weight | 503.55 |
| Synonyms | NCD |
| SMILES | O=C(NC1=NC2=C(C=C1)C=CC(C)=N2)OCCCNCCCOC(NC3=NC4=C(C=C3)C=CC(C)=N4)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.