Fig. 1 · Structure

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NaPi2b-IN-1

NaPi2b Inhibitor

NaPi2b-IN-1 is a selective inhibitor of the sodium-dependent phosphate transport protein 2b (NaPi2b), exhibiting an IC50 of 64 nM. Primarily expressed in the small intestine, lungs, and testes, NaPi2b is crucial for maintaining phosphate balance in the body. This compound is valuable for research into hyperphosphatemia and for elucidating the role of phosphate transport in various physiological and pathological processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1453116-06-7
Applications NaPi2b Inhibitor
Formula C44H58ClF3N4O11S
Molecular Weight 943.46
SMILES
FC(F)(F)C(C=C1/C=N/NC(C2=C(NC(C3=CC(COCCOCCOCCOCCOCCOCCN(CC(O)=O)CCOC)=CC=C3)=O)SC4=C2CCC(C)(C)C4)=O)=C(C=C1)Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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