Fig. 1 · Structure

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NaPi2b-IN-3

NaPi2b Inhibitor

NaPi2b-IN-3 is a potent inhibitor of the sodium-dependent phosphate transporter 2b (SLC34A2, NaPi2b), exhibiting IC50 values of 71 nM for human NaPi2b and 28 nM for rat NaPi2b. This compound is valuable for research applications focused on hyperphosphatemia, aiding the exploration of phosphate transport mechanisms and potential therapeutic interventions. Its selectivity makes it an essential tool for studying NaPi2b-related pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2227443-66-3
Applications NaPi2b Inhibitor
Formula C45H51N5O7
Molecular Weight 773.92
SMILES
CCC(N(CC1=CC(C(NC2=C(C3=C(N2)C=CC=C3)C(NC4=CC=C(C=C4)CCCC5=CC=C(C=C5)C(O)=O)=O)=O)=CC=C1)CCN(C(CCC(O)=O)=O)C)CC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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