Fig. 1 · Structure
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Naproxen-d3
Stable Isotope
Naproxen-d3 is a deuterated derivative of Naproxen, primarily known for its role as a COX-1 and COX-2 inhibitor, exhibiting IC50 values of 8.72 μM and 5.15 μM, respectively, in cellular assays. This stable isotope is ideal for pharmacokinetic studies and metabolic research, enabling precise tracking of drug metabolism and distribution in biological systems. Its use is critical in the development of therapeutic agents targeting inflammation and pain management.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1094102-82-5 |
| Applications | Stable Isotope |
| Formula | C14H11D3O3 |
| Molecular Weight | 233.28 |
| Synonyms | (S)-Naproxen-d3 |
| SMILES | OC([C@H](C1=CC2=C(C=C1)C=C(C=C2)OC([2H])([2H])[2H])C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.