NaV1.2/1.6 channel blocker-1 is a selective inhibitor of the NaV1.2 and NaV1.6 sodium channels, exhibiting IC50 values of 9.8 μM for rNaV1.6 and 24.4 μM for hNaV1.2. This compound is valuable for studying the role of sodium channels in neuronal excitability and has potential applications in the research of generalized epilepsy.
NaV1.2/1.6 channel blocker-1 is a selective inhibitor of the NaV1.2 and NaV1.6 sodium channels, exhibiting IC50 values of 9.8 μM for rNaV1.6 and 24.4 μM for hNaV1.2. This compound is valuable for studying the role of sodium channels in neuronal excitability and has potential applications in the research of generalized epilepsy.
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