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NB-7

SARM1 Inhibitor

NB-7 is a potent and orally active inhibitor of SARM1 (sterile alpha and TIR motif-containing protein 1), exhibiting an IC50 of less than 1 μM. This compound is utilized in research focused on neurological disorders, providing valuable insights into SARM1's role in neurodegeneration and related pathways. Its effectiveness makes NB-7 a crucial tool for exploring therapeutic strategies targeting SARM1 in various neurological contexts.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2665712-31-0
Applications	SARM1 Inhibitor
Formula	C₁₈H₁₇ClN₄O
Molecular Weight	340.81
SMILES	O=C(NC1=C(C)C(C2=CC=NC=C2)=NN1)CCC3=CC=C(Cl)C=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.