Fig. 1 · Structure
Documents & Downloads
NC-182
DNA Insertion Agent
NC-182 is a DNA intercalator that preferentially binds to B-form DNA, functioning as an effective anti-tumor agent. It promotes the conversion of Z-form DNA to B-form, enhancing its utility in various applications. NC-182 demonstrates robust inhibitory effects against both multidrug-resistant and sensitive tumor cells, making it a valuable tool in cancer research and therapeutic studies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 106224-67-3 |
| Applications | DNA Insertion Agent |
| Formula | C24H24N4O5 |
| Molecular Weight | 448.47 |
| SMILES | O=C(OC)C1=CC2=NC3=C(C(O)=C4C(C=CC=C4)=C3N=C2C=C1OC)C(NCCN(C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.