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NCFP

Catalog No.: A61922
mGlu5 modulator
NCFP is a positive allosteric modulator of metabotropic glutamate receptor 5 (mGlu5). This compound enhances the receptor's activity, making it valuable for investigating therapeutic avenues in central nervous system diseases. Its role in modulating mGlu5 function highlights its potential in understanding neurological disorders and developing novel treatments.
NCFP 774548-65-1 mGlu5 modulator
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNCFP is a positive allosteric modulator of metabotropic glutamate receptor 5 (mGlu5). This compound enhances the receptor's activity, making it valuable for investigating therapeutic avenues in central nervous system diseases. Its role in modulating mGlu5 function highlights its potential in understanding neurological disorders and developing novel treatments.
Product Information
Catalog NumA61922
FormulaC21H13ClFN3O3
Molecular Weight409.80
CAS Number774548-65-1
SMILESO=C(C1=NC=CC=C1)NC2=CC=C(Cl)C=C2CN(C(C3=C4C=CC=C3F)=O)C4=O
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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GPCR/G Protein > Metabotropic glutamate receptors (mGluR)