Fig. 1 · Structure

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NCGC00238624

GALK1 Inhibitor

NCGC00238624 is a selective inhibitor of galactokinase (GALK1), exhibiting IC50 values of 7.69 μM and 13.67 μM for human and mouse recombinant GALK1, respectively. This compound demonstrates minimal activity against GALK2 and other kinases at a concentration of 10 μM. NCGC00238624 serves as a valuable tool for investigating classic galactosemia and related metabolic pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2768230-55-1
Applications GALK1 Inhibitor
Formula C18H15ClN6O2
Molecular Weight 382.80
SMILES
O=C1C2=C(CCC1)NC(NC3=NC4=CC=CC=C4O3)=N[C@H]2C5=NNC=C5Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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