Fig. 1 · Structure
Documents & Downloads
NCGC00249987
Eya2 Inhibitor
NCGC00249987 is a selective allosteric inhibitor of the Eya2 tyrosine phosphatase, exhibiting IC50 values of 3 μM for the Eya2 enzymatic domain and 6.9 μM for full-length Eya2. This compound has been shown to effectively inhibit migration, invadopodia formation, and invasion in lung cancer cells. NCGC00249987 serves as a valuable tool for studying Eya2's role in cancer progression and cell signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1384864-80-5 |
| Applications | Eya2 Inhibitor |
| Formula | C16H11FN4O2S |
| Molecular Weight | 342.35 |
| SMILES | FC1=CC=CC(C(N/N=C/C(O2)=CC=C2SC3=NC=CC=N3)=O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.