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NCI-14465

ENPP1 Inhibitor

NCI-14465 is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) with an IC50 of 26.4 μM. This compound is utilized in cancer research to investigate the role of ENPP1 in tumor biology and potential therapeutic applications. Its inhibition of ENPP1 contributes to understanding nucleotide metabolism and signaling pathways in cancer cells.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1144534-31-5
Applications	ENPP1 Inhibitor
Formula	C₂₀H₁₉ClN₆
Molecular Weight	378.86
SMILES	NC1=NC(NC2=CC=C3C=CC=CC3=C2)=NC(NC4=CC=C(C)C=C4)=N1.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.