Fig. 1 · Structure
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NCT-504
PIP4Kγ Inhibitor
NCT-504 is a selective allosteric inhibitor of PIP4Kγ, demonstrating an IC50 value of 15.8 µM. This compound has potential applications in the research of Huntington's disease, providing insights into the molecular mechanisms and therapeutic strategies associated with the condition. NCT-504 may serve as a valuable tool for studying the role of PIP4Kγ in neurodegenerative processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1222765-97-0 |
| Applications | PIP4Kγ Inhibitor |
| Formula | C15H12N6O2S3 |
| Molecular Weight | 404.49 |
| SMILES | CN1N=NN=C1SC2=C(C(C3=CC=CC(S(=O)(C)=O)=C3)=CS4)C4=NC=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.