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ND-646

Catalog No.: A20079

ACC inhibitor

ND-646

ND-646 Chemical Structure

CAS NO. 1434639-57-2

ND-646 is an orally bioavailable and steric inhibitor of acetyl-CoA carboxylase (ACC) with IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively.

Availability: In stock

Package Price Qty
1 mg
$200.00
5 mg
$500.00
10 mg
$700.00
50 mg
$1,800.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

ND-646 is an orally bioavailable and steric inhibitor of acetyl-CoA carboxylase (ACC) with IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.59 mL 87.93 mL 175.86 mL
0.5 mM 3.52 mL 17.59 mL 35.17 mL
1 mM 1.76 mL 8.79 mL 17.59 mL
5 mM 0.35 mL 1.76 mL 3.52 mL

*The above data is based on the productmolecular weight 568.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20079
Actions Inhibitor
CAS No. 1434639-57-2
Formula C28H32N4O7S
M. Wt 568.64
Purity >98%
Synonyms ND 646; ND646
SMILES O=C(N)C(C)(C)N(C(N(C[C@@H](C1=CC=CC=C1OC)OC2CCOCC2)C3=C4C(C)=C(C5=NC=CO5)S3)=O)C4=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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