NDH-1 inhibitor-1 is a selective inhibitor targeting the NADH dehydrogenase-1 (NDH-1) enzyme, showing pI50 values of <4, 5.40, and 6.15 µM for bovine submitochondrial particles, potato submitochondrial particles, and Escherichia coli, respectively. This compound is useful for investigating the role of NDH-1 in cellular respiration and energy production. It serves as a valuable tool for researchers studying mitochondrial function and related metabolic pathways in various biological systems.
Fig. 1 · Structure
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NDH-1 inhibitor-1
NDH-1 Inhibitor
NDH-1 inhibitor-1 is a selective inhibitor targeting the NADH dehydrogenase-1 (NDH-1) enzyme, showing pI50 values of <4, 5.40, and 6.15 µM for bovine submitochondrial particles, potato submitochondrial particles, and Escherichia coli, respectively. This compound is useful for investigating the role of NDH-1 in cellular respiration and energy production. It serves as a valuable tool for researchers studying mitochondrial function and related metabolic pathways in various biological systems.
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 173964-49-3 |
| Applications | NDH-1 Inhibitor |
| Formula | C20H19NO3 |
| Molecular Weight | 321.37 |
| SMILES | O=C(C1=CC=C2C=CC=CC2=C1)NCC3=CC=C(OC)C(OC)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.