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NE58043

Bisphosphonate Compound

NE58043 is a nitrogen-containing bisphosphonate compound primarily targeting bone metabolism. It exhibits notable cytotoxicity with an LD50 of 171 μM against human nasopharyngeal carcinoma KB cells, while demonstrating minimal inhibitory activity against Entamoeba histolytica and Plasmodium falciparum, with IC50 values exceeding 200 μM. This compound is relevant for research applications focusing on cancer and infection, particularly in studying nasopharyngeal carcinoma.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	105462-25-7
Applications	Bisphosphonate Compound
Formula	C₇H₁₁NO₇P₂
Molecular Weight	283.11
SMILES	O=P(O)(O)C(O)(CC=1C=CN=CC1)P(=O)(O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.