Nec-4

Catalog No.: A21033

RIP1 inhibitor

Nec-4

Nec-4 Chemical Structure

CAS NO. 1041644-43-2

Nec-4, a tricyclic derivative, is a potent receptor interacting protein 1 (RIP1) inhibitor, with an IC50 of 2.6 μM, Ki of 0.46 μM.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

Nec-4, a tricyclic derivative, is a potent receptor interacting protein 1 (RIP1) inhibitor, with an IC50 of 2.6 μM, Ki of 0.46 μM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.71 mL 163.54 mL 327.09 mL
0.5 mM 6.54 mL 32.71 mL 65.42 mL
1 mM 3.27 mL 16.35 mL 32.71 mL
5 mM 0.65 mL 3.27 mL 6.54 mL

*The above data is based on the productmolecular weight 305.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21033
Actions Inhibitor
CAS No. 1041644-43-2
Formula C15H13ClFN3O
M. Wt 305.73
Solubility DMSO
Purity >98%
Synonyms Nec4
SMILES C[[email protected]@H](C1=C(C=CC=C1Cl)F)NC(C2=CC=C(N2C)C#N)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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