Fig. 1 · Structure
Documents & Downloads
Nedosiran sodium
RNA Interference Agent
Nedosiran sodium is an RNA interference agent that targets lactate dehydrogenase (LDH). This GalNAc-dsRNA conjugate demonstrates significant potential as a therapeutic option for primary hyperoxaluria (PH), particularly in patients with end-stage renal disease (ESRD). Its mechanism of action offers a novel approach to reducing LDH levels, thereby addressing metabolic imbalances associated with these conditions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2247026-22-6 |
| Applications | RNA Interference Agent |
| Formula | C662H865F19N231O413P57S6.xNa |
| Molecular Weight | 20985 (free acid) |
| Synonyms | DCR-PHXC sodium |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.