Fig. 1 · Structure

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Nef ligand-2

Ligands for E3 Ligase

Nef ligand-2 is a specific ligand for the Nef protein, functioning primarily as a binder that targets E3 ligases. It plays a crucial role in modulating protein interactions and degradation pathways, offering valuable insights into Nef-related signaling mechanisms. This compound is particularly relevant in research applications focused on HIV pathogenesis and the exploration of therapeutic strategies targeting E3 ligase activity.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 3066896-28-1
Applications Ligands for E3 Ligase
Formula C27H20ClF3N4O4
Molecular Weight 556.92
SMILES
O=C(COC1=CC=C(CCC2=C(O)N(C3=NC4=C(N3)C=C(Cl)C=C4)N=C2C5=CC=C(C(F)(F)F)C=C5)C=C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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