Nef ligand-2

Catalog No.: A51612
Ligands for E3 Ligase
Nef ligand-2 is a specific ligand for the Nef protein, functioning primarily as a binder that targets E3 ligases. It plays a crucial role in modulating protein interactions and degradation pathways, offering valuable insights into Nef-related signaling mechanisms. This compound is particularly relevant in research applications focused on HIV pathogenesis and the exploration of therapeutic strategies targeting E3 ligase activity.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNef ligand-2 is a specific ligand for the Nef protein, functioning primarily as a binder that targets E3 ligases. It plays a crucial role in modulating protein interactions and degradation pathways, offering valuable insights into Nef-related signaling mechanisms. This compound is particularly relevant in research applications focused on HIV pathogenesis and the exploration of therapeutic strategies targeting E3 ligase activity.
Product Information
Catalog NumA51612
FormulaC27H20ClF3N4O4
Molecular Weight556.92
CAS Number3066896-28-1
SMILESO=C(COC1=CC=C(CCC2=C(O)N(C3=NC4=C(N3)C=C(Cl)C=C4)N=C2C5=CC=C(C(F)(F)F)C=C5)C=C1)O
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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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