Fig. 1 · Structure
Documents & Downloads
Nelutroctiv
Cardiac Troponin Activator
Nelutroctiv is a selective cardiac troponin activator that enhances cardiac contractility by increasing the sensitivity of troponin to calcium ions and promoting actin-myosin interaction in cardiac sarcomeres. This orally active compound is particularly valuable in the study of cardiovascular diseases characterized by impaired cardiac contractile function. Research applications include investigating therapeutic strategies aimed at improving cardiac performance in various heart conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 2299177-09-4 |
| Applications | Cardiac Troponin Activator |
| Formula | C24H22F5N3O4S |
| Molecular Weight | 543.51 |
| Synonyms | CK-136 |
| SMILES | O=C(C1=CN=CC(S(C)(=O)=O)=C1)N2[C@@]3([H])[C@](C[C@@H]2C(N[C@H](C4CC4)C5=C(C=C(C(F)=C5)C(F)(F)F)F)=O)([H])C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.