Nemorexant

Catalog No.: A12685

orexin receptor antagonist

Nemorexant

Nemorexant Chemical Structure

CAS NO. 1505484-82-1

Nemorexant (ACT-541468) is a potent orexin receptor antagonist extracted from patent WO2015083094A1, compound example 7, has IC50s of 2 nM and 3 nM for Ox1 receptor and Ox2 receptor, respectively.

Availability: In stock

Package Price Qty
1 mg
$90.00
5 mg
$270.00
10 mg
$460.00
50 mg
$1,380.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Nemorexant (ACT-541468) is a potent orexin receptor antagonist extracted from patent WO2015083094A1, compound example 7, has IC50s of 2 nM and 3 nM for Ox1 receptor and Ox2 receptor, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.18 mL 110.88 mL 221.77 mL
0.5 mM 4.44 mL 22.18 mL 44.35 mL
1 mM 2.22 mL 11.09 mL 22.18 mL
5 mM 0.44 mL 2.22 mL 4.44 mL

*The above data is based on the productmolecular weight 450.92. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12685
Actions Antagonist
M. Wt 450.92
Formula C23H23ClN6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1505484-82-1
Synonyms ACT-541468, ACT 541468, ACT541468
SMILES C[[email protected]](CCC1)(C2=NC3=CC=C(Cl)C(C)=C3N2)N1C(C4=C(N5N=CC=N5)C=CC(OC)=C4)=O

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