Fig. 1 · Structure

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Neoantimycin

GRP78/BiP/Ras Modulator

Neoantimycin is a regulator of GRP78/BiP and K-Ras, demonstrating significant anticancer activity. This compound is biosynthesized through a hybrid nonribosomal peptide synthetase/polyketide synthase (NRPS/PKS) system, making it a valuable tool for studying cancer biology and therapeutic interventions. Its modulation of cellular stress responses and oncogenic pathways positions Neoantimycin as a potential candidate for research in cancer treatment and drug discovery.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 22862-63-1
Applications GRP78/BiP/Ras Modulator
Formula C36H46N2O12
Molecular Weight 698.76
SMILES
O=C(C1=C(C(NC=O)=CC=C1)O)N[C@@H]2C(O[C@H](C(O[C@@H]([C@@H](C(C)(C(O[C@@](C(O[C@@H]2C)=O)([H])[C@@H](C)CC)=O)C)O)CC3=CC=CC=C3)=O)C(C)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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