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Nepicastat (free base) (SYN-117)

dopamine beta-hydroxylase inhibitor

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Catalog No. A10637

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Nepicastat 5mg A10637-5
Nepicastat 10mg A10637-10
Nepicastat 50mg A10637-50
Nepicastat 100mg A10637-100

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Quick Overview

Nepicastat is an inhibitor of dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine.

Nepicastat (free base) (SYN-117)

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Chemical Information

Catalog Num A10637
Actions Inhibitor
M. Wt 295.4
Formula C14H15F2N3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 173997-05-2
Synonyms RS-25560-197, SYN117
SMILES C1CC2=C(C=C(C=C2C[[email protected]]1N3C(=CNC3=S)CN)F)F

Biological Activity

Nepicastat is an inhibitor of dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.85 mL 169.26 mL 338.52mL
0.5 mM 6.77 mL 33.85 mL 67.7 mL
1 mM 3.39 mL 16.93 mL 33.85 mL
5 mM 0.68 mL 3.39 mL 6.77 mL

*The above data is based on the productmolecular weight 295.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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