Fig. 1 · Structure

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Nepinalone hydrochloride

Cough Suppressant

Nepinalone hydrochloride is an alkylaminate derivative of β-tetralone that functions as an orally active cough suppressant. It exhibits non-opioid antitussive activity, making it suitable for research focused on respiratory conditions and the mechanisms of cough reflex modulation. This compound may serve as a valuable tool in the investigation of alternative therapies for managing cough without the side effects associated with opioid treatments.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 22443-55-6
Applications Cough Suppressant
Formula C18H26ClNO
Molecular Weight 307.86
SMILES
[H]Cl.CC1(C2=CC=CC=C2CCC1=O)CCN3CCCCC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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