Neratinib (HKI-272)

Name: Neratinib (HKI-272)
SKU: A10638
Price: 25 USD
Rating: 5 (3 reviews)

Catalog No.: A10638

HER2 inhibitor

Adooq's Neratinib (HKI-272) has been cited by 3 publications

Neratinib (HKI-272) is a tyrosine kinase inhibitor.

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Grouped product items
Size	Price	Stock
5mg	$25.00	In stock
10mg	$35.00	In stock
25mg	$55.00	In stock
50mg	$80.00	In stock
100mg	$120.00	In stock
200mg	$190.00	In stock
500mg	$320.00	In stock
Bulk Size	Bulk Discount

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Data Sheet

SDS

Adooq Products cited in reputable paper

Adooq's Neratinib (HKI-272) has been cited by 3 publications

Majid Momeny, .et al. , EMBO Mol Med, 2024, Jun 17 PMID: 38886591

Hamzehlou S, .et al. , Eur J Pharmacol, 2019, Nov 15;863:172705 PMID: 31574259

Li Li, .et al. , Leukemia Res, 2019, 78:12-20 PMID: 30660961

Biological Activity

Discription

Neratinib (HKI-272) is a tyrosine kinase inhibitor.

Targets

Target	Value

Product Information

Catalog Num	A10638
Formula	C30H29ClN6O3
Molecular Weight	557
CAS Number	698387-09-6
SMILES	CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/CN(C)C
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	Warmed: 4 mg/mL (7.18 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.95 mL	89.77 mL	179.53 mL
0.5 mM	3.59 mL	17.95 mL	35.91 mL
1 mM	1.8 mL	8.98 mL	17.95 mL
5 mM	0.36 mL	1.8 mL	3.59 mL

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