Neratinib (HKI-272)

Neratinib (HKI-272) is a tyrosine kinase inhibitor.
Grouped product items
Product Name Price Stock Qty
Neratinib 5mg
$30.00
In stock
Neratinib 10mg
$50.00
In stock
Neratinib 25mg
$75.00
In stock
Neratinib 100mg
$140.00
In stock
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Adooq Products cited in reputable paper
Adooq's Neratinib (HKI-272) has been cited by 3 publications
  • Majid Momeny, .et al. , EMBO Mol Med, 2024, Jun 17 PMID: 38886591
  • Hamzehlou S, .et al. , Eur J Pharmacol, 2019, Nov 15;863:172705 PMID: 31574259
  • Li Li, .et al. , Leukemia Res, 2019, 78:12-20 PMID: 30660961
  • Biological Activity
    Discription Neratinib (HKI-272) is a tyrosine kinase inhibitor.
    Targets
    Target Value
    Product Information
    Catalog Num A10638
    Formula C30H29ClN6O3
    Molecular Weight 557
    CAS Number 698387-09-6
    SMILES CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/CN(C)C
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 4 mg/mL (7.18 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 17.95 mL 89.77 mL 179.53 mL
    0.5 mM 3.59 mL 17.95 mL 35.91 mL
    1 mM 1.8 mL 8.98 mL 17.95 mL
    5 mM 0.36 mL 1.8 mL 3.59 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
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