Fig. 1 · Structure
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NESS 0327
Cannabinoid Antagonist
NESS 0327 is a selective cannabinoid antagonist targeting the cannabinoid CB1 receptor with over 60,000-fold specificity. This high selectivity makes NESS 0327 a valuable tool for studying CB1 receptor-related biological pathways and understanding the role of cannabinoids in various physiological and pathological processes. Its use in research can provide insights into potential therapeutic applications in conditions influenced by the endocannabinoid system.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 494844-07-4 |
| Applications | Cannabinoid Antagonist |
| Formula | C24H23Cl3N4O |
| Molecular Weight | 489.82 |
| SMILES | O=C(C1=NN(C2=CC=C(Cl)C=C2Cl)C3=C1CCCC4=CC(Cl)=CC=C43)NN5CCCCC5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.