Fig. 1 · Structure

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Neutrophil elastase inhibitor 1

Elastase Inhibitor

Neutrophil elastase inhibitor 1 is a competitive, pseudoirreversible inhibitor primarily targeting neutrophil elastase. With an IC50 value of 7 nM, it effectively modulates elastase activity, making it a valuable tool in the study of inflammatory diseases where neutrophil activation plays a crucial role. This compound can facilitate research into therapeutic interventions for conditions characterized by excessive elastase activity.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1448314-31-5
Applications Elastase Inhibitor
Formula C16H11N3O
Molecular Weight 261.28
SMILES
N#CC1=NN(C2=C1C=CC=C2)C(C3=CC=CC(C)=C3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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