Fig. 1 · Structure

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Nevadistinel

iGluR Modulator

Nevadistinel is a positive allosteric modulator of the N-methyl-D-aspartate (NMDA) receptor, targeting excitatory neurotransmission. It demonstrates potential neuroprotective effects by mitigating cognitive impairment associated with various neurodegenerative conditions, including mild cognitive impairment, Alzheimer's disease, Parkinson's disease, and Lewy body disease. This compound can serve as a valuable tool in research aimed at understanding and treating cognitive deficits in these disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 2181816-92-0
Applications iGluR Modulator
Formula C15H18N2O3
Molecular Weight 274.32
Synonyms NYX-458; NYX-3054
SMILES
O=C1[C@@]2(CC(NCC2)=O)CN1CC3=CC=C(C=C3)OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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