Fig. 1 · Structure
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Nevirapine-d4
Deuterium Labeled Nevirapine
Nevirapine-d4 is a deuterium-labeled derivative of Nevirapine, a non-nucleoside inhibitor targeting HIV-1 reverse transcriptase. This compound is utilized in research to study the pharmacokinetics and metabolic pathways of Nevirapine, enhancing understanding of its biological activity in the context of HIV/AIDS treatment and prevention. With a potency characterized by a Ki value of 270 μM, Nevirapine-d4 serves as a valuable tool in mechanistic studies and drug development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1051418-95-1 |
| Applications | Deuterium Labeled Nevirapine |
| Formula | C15H10D4N4O |
| Molecular Weight | 270.32 |
| SMILES | O=C1C2=CC=CN=C2N(C3C([2H])([2H])C3([2H])[2H])C4=NC=CC(C)=C4N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.