Fig. 1 · Structure
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NF546
P2Y11 Agonist
NF546 is a selective non-nucleotide agonist of the P2Y11 receptor, exhibiting a pEC50 of 6.27. This compound effectively stimulates the release of interleukin-8 from human monocyte-derived dendritic cells, making it valuable for research focused on immune response modulation and inflammation pathways. Its targeted action on P2Y11 highlights its potential in studying purinergic signaling and associated biological functions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1006028-37-0 |
| Applications | P2Y11 Agonist |
| Formula | C47H44N6Na4O17P4 |
| Molecular Weight | 1180.74 |
| SMILES | O=P(O)(O[Na])CC1=C(C=CC(CP(O)(O[Na])=O)=C1)NC(C2=CC(NC(C3=CC(NC(NC4=CC(C(NC5=CC(C(NC6=C(C=C(CP(O)(O[Na])=O)C=C6)CP(O)(O[Na])=O)=O)=CC=C5C)=O)=CC=C4)=O)=CC=C3)=O)=C(C)C=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.