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NFE2L1 activator-1

NFE2L1 Activator

NFE2L1 activator-1 is a potent activator of nuclear factor erythroid 2-related factor 1 (NFE2L1), exhibiting an EC50 of 2.4 µM. This compound effectively combats ferroptosis by specifically activating the NFE2L1 signaling pathway, leading to the upregulation of glutathione peroxidase 4 (GPX4). NFE2L1 activator-1 is suitable for research applications focused on cancer biology and investigating oxidative stress responses.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Activator
CAS Number	3070514-51-8
Applications	NFE2L1 Activator
Formula	C₂₆H₃₁NO₇S
Molecular Weight	501.59
SMILES	COC1=C(OC)C=CC(/C=C2CC(NS(=O)(CC)=O)C/C(C\2=O)=C\C3=CC=C(OC)C(OC)=C3)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.