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NFE2L2 activator 3

NFE2L2 Activator

NFE2L2 Activator 3 is a potent NFE2L2/NRF2 activator, primarily functioning by specifically stimulating the NAD(P)H:quinone oxidoreductase (NQO1) enzyme, with an EC50 of less than 1 nM. This compound is essential for investigations into the biological pathways related to oxidative stress and its role in respiratory system diseases, including chronic obstructive pulmonary disease. NFE2L2 Activator 3 serves as a valuable tool for elucidating the mechanisms underlying cellular protection and inflammatory responses in various research settings.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Activator
CAS Number	2230581-03-8
Applications	NFE2L2 Activator
Formula	C₂₉H₃₃ClN₄O₅S₂
Molecular Weight	617.18
SMILES	[C@@H]([C@](C(O)=O)(C)C)(C=1C(C)=C2C(=CC1)N(CC)N=N2)C3=CC(CN4S(=O)(=O)C=5C(O[C@H](CC)C4)=CC=CC5)=C(Cl)S3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.