Documents & Downloads

NH2-Gly-PAB-Exatecan-D-glucuronic acid

ADC Drug-Linker Conjugate Precursor

NH2-Gly-PAB-Exatecan-D-glucuronic acid is an ADC drug-linker conjugate precursor that effectively reacts with NHS groups to facilitate the formation of drug-linker conjugates. This compound is instrumental in the development of antibody-drug conjugates (ADCs), enhancing targeted delivery of therapeutic agents. Its key biological activity lies in enabling the construction of linkers that can improve the efficacy and selectivity of cancer treatments. This reagent is essential for researchers focusing on ADC technology and drug delivery systems.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
CAS Number	2763252-31-7
Applications	ADC Drug-Linker Conjugate Precursor
Formula	C₄₀H₄₀FN₅O₁₄
Molecular Weight	833.77
SMILES	NCC(NC(C=C1COC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=C(C=C1)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)C(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.