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NHS-Modified MMAF

Intermediate

NHS-Modified MMAF is an intermediate that serves as a crucial component in the synthesis of antibody-drug conjugates (ADCs) targeting mesothelin. This compound facilitates the conjugation of therapeutic agents to monoclonal antibodies, enhancing the specificity and efficacy in targeting mesothelin-expressing tumors. Applications include research in targeted cancer therapy and development of new therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1404073-10-4
Applications	Intermediate
Formula	C₅₅H₈₆N₈O₁₂
Molecular Weight	1051.32
SMILES	O=C(N1CCCCO1)[C@@H](NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)CCCCCC(ON3C(CCC3=O)=O)=O)=O)=O)=O)OC)=O)CC4=CNC5=CC=CC=C45

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.