Fig. 1 · Structure

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Niclosamide-13C6 monohydrate

Stable Isotope

Niclosamide-13C6 monohydrate is a stable isotope-labeled form of Niclosamide, an orally active antihelminthic agent. This compound functions as a STAT3 inhibitor, exhibiting an IC50 of 0.25 μM in HeLa cells. Niclosamide-13C6 monohydrate demonstrates significant biological activity against various cancer types and has been shown to inhibit DNA replication in Vero E6 cells, making it valuable for research in cancer biology and parasitology.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1325559-12-3
Applications Stable Isotope
Formula C713C6H10Cl2N2O5
Molecular Weight 351.09
Synonyms BAY2353-13C6 monohydrate
SMILES
Cl[13C]([13CH]=[13C]([13CH]=[13CH]1)[N+]([O-])=O)=[13C]1NC(C2=C(C=CC(Cl)=C2)O)=O.O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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