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Niclosamide-d3

Stable Isotope

Niclosamide-d3 is a deuterium-labeled derivative of Niclosamide, primarily functioning as a stable isotope. This compound serves as an orally active antihelminthic agent and is extensively utilized in research related to parasitic infections. Additionally, Niclosamide demonstrates significant biological activity as a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells, and has been shown to inhibit DNA replication in Vero E6 cells, making it a valuable tool in cancer research applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2665663-60-3
Applications	Stable Isotope
Formula	C₁₃H₅D₃Cl₂N₂O₄
Molecular Weight	330.14
Synonyms	BAY2353-d3
SMILES	O=C(NC1=C([2H])C([2H])=C([N+]([O-])=O)C([2H])=C1Cl)C2=CC(Cl)=CC=C2O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.