Fig. 1 · Structure
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Niclosamide monohydrate
Antihelminthic Agent
Niclosamide monohydrate is an orally active antihelminthic agent with significant applications in parasitic infection research. Primarily recognized as a STAT3 inhibitor, it exhibits an IC50 of 0.25 μM in HeLa cells and demonstrates notable anti-cancer properties. Additionally, Niclosamide monohydrate has been shown to inhibit DNA replication in Vero E6 cells, making it a valuable compound for various biological studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 73360-56-2 |
| Applications | Antihelminthic Agent |
| Formula | C13H10Cl2N2O5 |
| Molecular Weight | 345.13 |
| Synonyms | BAY2353 monohydrate |
| SMILES | O=C(NC1=CC=C([N+]([O-])=O)C=C1Cl)C2=CC(Cl)=CC=C2O.O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.