Fig. 1 · Structure

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Niclosamide sodium

Antihelminthic Agent

Niclosamide sodium is an orally active antihelminthic agent that targets the modulation of STAT3 signaling pathways. With an IC50 of 0.25 µM in HeLa cells, it exhibits significant biological activities against various cancer types. Additionally, Niclosamide sodium has been shown to inhibit DNA replication in Vero E6 cells, making it a valuable compound for research into both parasitic infections and cancer therapeutics.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 40321-86-6
Applications Antihelminthic Agent
Formula C13H7Cl2N2NaO4
Molecular Weight 349.10
Synonyms BAY2353 sodium
SMILES
O=C(NC1=CC=C([N+]([O-])=O)C=C1Cl)C2=CC(Cl)=CC=C2O[Na]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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