Nicotelline is a nicotine-related alkaloid that serves as a weak inhibitor of cytochrome P-450 2A6 (CYP2A6), an enzyme involved in the metabolism of coumarin. Although Nicotelline shows limited inhibitory activity at concentrations up to 300 μM, it possesses potential utility as a biomarker for particulate matter (PM) sourced from tobacco smoke. This compound is valuable for research in toxicology and nicotine metabolism studies.
Nicotelline is a nicotine-related alkaloid that serves as a weak inhibitor of cytochrome P-450 2A6 (CYP2A6), an enzyme involved in the metabolism of coumarin. Although Nicotelline shows limited inhibitory activity at concentrations up to 300 μM, it possesses potential utility as a biomarker for particulate matter (PM) sourced from tobacco smoke. This compound is valuable for research in toxicology and nicotine metabolism studies.
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