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Nicotinamide-15N

Stable Isotope

Nicotinamide-15N is a stable isotope-labeled form of Nicotinamide, a derivative of vitamin B3. This compound selectively inhibits SIRT1 and SIRT2 activities, with an IC50 of 2 μM for SIRT2. Nicotinamide-15N enhances cellular levels of NAD+, ATP, and reactive oxygen species (ROS), demonstrating potential for suppressing tumor growth and improving survival rates. Additionally, it exhibits anti-HBV activity, making it valuable for studies in cancer research and viral infections.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	113950-01-9
Applications	Stable Isotope
Formula	C₆H₆N₁₅NO
Molecular Weight	123.12
Synonyms	Niacinamide-15N; Nicotinic acid amide-15N
SMILES	[15NH2]C(C1=CN=CC=C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.